Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of an Improved Reactive Mercury Active System: Uncertainties and Applicability in Polluted Environments.

Environmental science & technology·2026
Same author

Defect-Mediated Sonodynamic Catalysis on Calcium-Deficient Hydroxyapatite Nanoparticles Coordinating Bacterial Elimination and Bone Regeneration against Osteomyelitis.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Dietary supplementation with fermented compound Chinese herbal medicine reshapes the gastrointestinal microbiota and enhances growth in suckling lambs.

Microbiology spectrum·2026
Same author

Glial high-mobility group box 1 translocation promotes post-stroke epileptic seizures.

Neurochemistry international·2026
Same author

The Effect of Electropulsing-Assisted Ultrasonic Surface Rolling Process on the Friction and Wear Properties of AA 2024-T3.

Micromachines·2026
Same author

The role and predictive potential of miR-451-5p in delayed fracture healing.

Cytotechnology·2026

Related Experiment Video

Updated: May 10, 2026

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde
07:04

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde

Published on: November 11, 2022

2.6K

Silver-Based Nanozyme Hydrogel with Enhanced Multienzyme Activity for Infected Wound Treatment.

Wenqi Wang1,2, Xiaolong Wei2, Hengshuo Gui2

  • 1School of Pharmaceutical Sciences, Anhui Medical University, Hefei, 230032, P. R. China.

Advanced Healthcare Materials
|September 4, 2025
PubMed
Summary
This summary is machine-generated.

This study developed a smart wound dressing using a silver-doped carbon carrier in a cationic guar matrix. The dressing effectively kills bacteria and promotes tissue healing by enhancing ROS burst and activating key cellular pathways.

Keywords:
Ag single atoms and nanoparticlesantibacterial and antibiofilmmultiple enzyme‐like activitieswound dressing

More Related Videos

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing
04:09

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing

Published on: December 13, 2024

742
Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management
09:17

Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management

Published on: February 28, 2025

418

Related Experiment Videos

Last Updated: May 10, 2026

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde
07:04

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde

Published on: November 11, 2022

2.6K
Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing
04:09

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing

Published on: December 13, 2024

742
Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management
09:17

Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management

Published on: February 28, 2025

418

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Wound Healing

Background:

  • Infected wounds require advanced antibacterial dressings for effective treatment.
  • Current treatments face challenges with bacterial resistance and suboptimal healing.
  • Developing multifunctional dressings is crucial for improved patient outcomes.

Purpose of the Study:

  • To create a novel smart wound dressing with synergistic antibacterial and healing-promoting properties.
  • To investigate the mechanism of action of a silver-doped carbon-based composite in a cationic guar matrix.
  • To evaluate the dressing's efficacy in combating bacterial biofilms and promoting tissue regeneration.

Main Methods:

  • Fabrication of a nitrogen-doped carbon-based silver single-atom/nanoparticle composite carrier (AgSA/NP-NC) anchored in a cationic guar matrix (CG).
  • Assessment of enhanced enzyme catalytic efficiencies (oxidase, peroxidase, glutathione peroxidase) due to AgSA/NP.
  • Investigation of the reactive oxygen species (ROS) burst mechanism, biofilm disintegration, and bacterial membrane permeability changes.
  • Mechanistic studies on the synergistic Ag+/ROS effect, oxidative stress, metabolic inhibition, and gene expression.
  • Evaluation of the dressing's impact on Wnt, MAPK, and PI3K-Akt signaling pathways for tissue regeneration.

Main Results:

  • The AgSA/NP-NC/CG dressing demonstrated enhanced antibacterial activity through a synergistic ROS burst mechanism.
  • Effective disintegration of bacterial biofilms and increased bacterial membrane permeability were observed.
  • The dressing induced an "oxidative stress-metabolic inhibition" cascade, leading to bacterial energy depletion and genetic damage.
  • Activation of Wnt, MAPK, and PI3K-Akt signaling pathways promoted cell proliferation, angiogenesis, and epidermal growth.
  • The dressing successfully remodeled the infection microenvironment, facilitating tissue regeneration.

Conclusions:

  • The developed smart wound dressing offers a systematic solution for infected wound treatment.
  • The synergistic antibacterial and tissue-regeneration functions provide a promising therapeutic strategy.
  • This multifunctional dressing holds potential for advancing wound care management.