Morel-Lavallée lesion: What you need to know
Nikta Sarani1, Amandeep Ahluwalia, Anna Buchanan
1From the Department of Surgery, Center for Trauma and Critical Care, George Washington University, Washington, DC.
The Journal of Trauma and Acute Care Surgery
|September 4, 2025
Summary
Morel-Lavallée lesions (MLL) are rare degloving injuries. Early diagnosis and varied treatments, from conservative to surgical, are key to managing these fluid-filled cavities and improving patient outcomes.
Area of Science:
- Orthopedic Surgery
- Traumatology
- Radiology
Background:
- Morel-Lavallée lesion (MLL) is a rare closed degloving injury caused by shearing forces.
- It involves separation of subcutaneous tissue from fascia, creating a cavity filled with fluid.
- Commonly affects areas with significant skin mobility over bony prominences, like the thigh.
Purpose of the Study:
- To provide a comprehensive overview of Morel-Lavallée lesions.
- To discuss diagnostic approaches, including clinical evaluation and advanced imaging.
- To review current and potential future treatment strategies for MLLs.
Main Methods:
- Systematic review of existing literature.
- Analysis of diagnostic criteria and imaging findings (MRI emphasized).
- Evaluation of conservative, minimally invasive, and surgical treatment modalities.
Main Results:
- Diagnosis is primarily clinical but aided by MRI for confirmation and staging.
- Treatment is tailored to lesion size, chronicity, and symptoms, ranging from aspiration to surgery.
- Lesions evolve through inflammation and fibrosis, impacting treatment decisions.
Conclusions:
- Effective management of MLLs requires a spectrum of treatment options.
- Standardized guidelines, advanced imaging, and rehabilitation are needed for optimal outcomes.
- Further research is crucial for improving early recognition and minimizing morbidity.


