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Acute Posterior Multifocal Placoid Pigment Epitheliopathy-Like Panuveitis Following Mpox Vaccination
Lucy M Lu1,2, Priya D Samalia1,3,4, Rachael L Niederer1,2
1Department of Ophthalmology, Te Whatu Ora Te Toka Tumai/Health New Zealand Auckland, Auckland, New Zealand.
Purpose:
To report a case of APMPPE-like panuveitis following mpox vaccination.
Methods:
Case report.
Results:
A 37-year-old Chinese man presented with bilateral anterior and intermediate uveitis, retinal vasculitis and unilateral acute posterior multifocal placoid pigment epitheliopathy (APMPPE) 2 weeks following JYNNEOS mpox vaccination. Investigations excluded infectious and systemic inflammatory causes. Multi-modal imaging revealed features consistent with APMPPE in the left eye. His symptoms and clinical signs improved with topical and systemic corticosteroid therapy with no recurrence off treatment over a 9-month follow-up.
Conclusion:
Clinicians should be aware of the possibility of APMPPE-like panuveitis as a rare ocular complication following the mpox vaccine.
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