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Anxiety: Overview

Anxiety: Overview

Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.

Post-traumatic Stress Disorder

Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...

Panic Disorder

Panic Disorder

Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...

Depression: Overview

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...

Generalized Anxiety Disorder

Generalized Anxiety Disorder

Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...

Anxiolytic Drugs: Overview

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Anxiolytic drugs are vital in managing anxiety disorders by effectively alleviating symptoms such as excessive fear, tachycardia, and tremors. There are several classes of anxiolytic medications, each with unique mechanisms of action and potential side effects.
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Related Experiment Video

Updated: Sep 9, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Postpartum anxiety: a state-of-the-art review.

Natalie Feldman¹, Alice Hibara², Jamie Ye³

¹Brigham and Women's Hospital, Department of Psychiatry, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.

The Lancet. Psychiatry

|September 4, 2025

Summary

Postpartum anxiety affects 12.3% of mothers globally, often linked to first-time motherhood and younger age. Cognitive behavioral therapy shows promise for treatment, but more research is needed.

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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

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Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

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Reducing State Anxiety Using Working Memory Maintenance

Published on: July 19, 2017

Area of Science:

Reproductive Health
Maternal Mental Health
Perinatal Psychiatry

Background:

Postpartum anxiety (PPA) is an emerging area of mental health research.
Increasing interest in PPA necessitates a comprehensive review of existing literature.
Understanding PPA is crucial for maternal and infant well-being.

Purpose of the Study:

To conduct a state-of-the-art review of postpartum anxiety literature.
To synthesize the current body of knowledge on postpartum anxiety.
To identify research gaps and call for coordinated study.

Main Methods:

Comprehensive literature survey on postpartum anxiety.
Synthesis of existing research findings.
Analysis of prevalence, risk factors, screening tools, and treatment options.

Main Results:

Estimated global prevalence of postpartum anxiety is 12.3%.
Associated with primiparity and younger maternal age.
Cognitive behavioral therapy shows promising evidence; pharmacotherapy is understudied.

Conclusions:

Postpartum anxiety has significant impacts on maternal mental health and offspring development.
Current screening tools have limitations for ongoing assessment.
Further research is critical to understand PPA biology, clinical features, and improve interventions.