Nurse-Led Quality Improvement Initiative to Reduce Medication Errors in Pediatric ICU

Shivani Kumari1, Arun Bansal2, Meenakshi Agnihotri1

  • 1College of Nursing, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Indian Pediatrics
|September 5, 2025
PubMed

Insights

A nurse-led medication errors bundle significantly reduced medication errors in a pediatric intensive care unit (PICU). This quality improvement initiative demonstrated a sustained decrease in medication errors (MEs), enhancing patient safety.

Area of Science:

  • Pediatric Intensive Care
  • Medication Safety
  • Quality Improvement

Background:

  • Medication errors (MEs) pose a significant risk in pediatric intensive care units (PICUs).
  • Effective interventions are needed to reduce the incidence and severity of MEs in this vulnerable population.

Purpose of the Study:

  • To evaluate a nurse-driven, context-specific medication errors bundle for reducing MEs by at least 50% in a PICU.
  • To assess the impact of the intervention on different categories of medication errors and staff awareness.

Main Methods:

  • A prospective, before-and-after quality improvement study was conducted in a 15-bedded multidisciplinary PICU in northern India.
  • The intervention involved a structured prescription format, nursing observation and administration charts, and drug incompatibility charts, implemented through Plan-Do-Study-Act (PDSA) cycles.
  • Medication errors were categorized and assessed for severity using the NCC MERP Index.

Main Results:

  • The overall medication error rate decreased from 8.5% to 2.9%.
  • Significant reductions were observed across prescription (13.1% to 3.8%), dispensing (12.2% to 5.2%), administration (3.8% to 1.9%), and monitoring errors (1.7% to 0%).
  • Most errors were intercepted before patient harm (NCC MERP Category B), and staff quality improvement awareness increased from 55.5% to 84%.

Conclusions:

  • A low-cost, nurse-led medication errors bundle effectively reduced MEs in a PICU setting.
  • The intervention demonstrated sustained improvement and has potential applicability in similar pediatric intensive care environments.
  • This study highlights the critical role of nursing leadership in implementing successful quality improvement initiatives for medication safety.
Abstract

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