Wearable Point-of-Care Biosensor for Biomolecular Assay in Health Monitoring.

Area of Science:

• Biomedical Engineering
• Materials Science
• Analytical Chemistry

Background:

• Wearable biosensors are crucial for preventive health monitoring.
• Point-of-care testing (POCT) has evolved significantly.
• Real-time bioanalysis enables early disease detection.

Purpose of the Study:

• To review the evolution of wearable biosensors for POCT.
• To examine materials, fabrication techniques, and applications.
• To highlight their potential in disease diagnosis and healthcare.

Main Methods:

• Review of supramolecular hydrogels and advanced materials.
• Analysis of innovative fabrication techniques.
• Assessment of real-world applications in continuous monitoring.

Main Results:

• Wearable biosensors demonstrate high sensitivity, specificity, and portability.
• Continuous monitoring of biomolecules in body fluids supports early diagnosis of infections, cardiovascular disorders, diabetes, and cancer.
• Integration with wireless technology and AI enhances clinical and remote healthcare applicability.

Conclusions:

• Wearable biosensors show significant potential for reducing healthcare costs and improving patient outcomes.
• Challenges include standardizing protocols, cost-effectiveness, and data privacy.
• Continued research is necessary to overcome limitations and advance wearable biosensor technology.