Related Experiment Video
Updated: Sep 8, 2025

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
Published on: April 11, 2025
Dynamic Changes of the S Wave in Lead V6: A Novel Visual Indicator for Left Bundle Branch Capture
Shanshan Zhuo1, Longfu Jiang1, Xiaojie Cai1
1Department of Cardiology, Ningbo No. 2 Hospital, Ningbo, Zhejiang, China.
Background:
During the electrode screwing process in left bundle branch pacing (LBBP), the significance of the S wave in lead V6 remains elusive. In this study we analyzed the change of the S wave in lead V6 under different patterns of capture and explore its mechanisms.
Methods:
Our study included 243 patients with selective LBBP (SLBBP). We used the continuous pacing technique and classified the electrophysiologic characteristics observed during the screwing process into 4 patterns: left ventricular septal pacing (LVSP), nonselective LBBP (NSLBBP) in low output and in lower output, and selective LBBP. The change of the S-wave morphology in lead V6 and R-wave peak time in leads V6 and V1 were evaluated according to these 4 patterns.
Results:
In all 243 cases, the presence of S wave in V6 gradually increased in the 4 patterns as follows: 35.4% in LVSP, 77.0% in NSLBBP low output, 82.7% in NSLBBP lower output, and 97.9% in SLBBP. From the LVSP to the NSLBBP (low output) pattern, there were 60 (69.8%) cases of deepening of the S wave and 101 (64.3%) cases showing a newly emerged S wave. From the NSLBBP lower output to the SLBBP pattern, there were 171 (85.1%) cases with a deepening S wave and 37 (88.1%) cases with a newly emerged S wave. Sensitivity and specificity of the S wave in lead V6 were 97.9% and 100% in SLBBP, respectively.
Conclusions:
The dynamically changing S wave in lead V6 serves as a novel visual indicator of left bundle branch capture.
More Related Videos
12:45Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
09:52Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts
Published on: November 7, 2019
Related Concept Videos
Electrocardiogram
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
Electrocardiogram Fundamentals
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
Assessment of apical radial pulse
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation
Cardiac Action Potential
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Correlation between ECG and Cardiac Cycle
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...