Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Equilibrium and Balance01:15

Equilibrium and Balance

5.0K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
5.0K
The Vestibular System01:29

The Vestibular System

40.2K
The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.
40.2K
Gyroscope: Precession01:24

Gyroscope: Precession

4.6K
Precession can be demonstrated effectively through a spinning top. If a spinning top is placed on a flat surface near the surface of the Earth at a vertical angle and is not spinning, it will fall over due to the force of gravity producing a torque acting on its center of mass. However, if the top is spinning on its axis, it precesses about the vertical direction, rather than topple over due to this torque. Precessional motion is a combination of a steady circular motion of the axis and the...
4.6K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

554
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
554
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

665
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
665

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cup-to-Disc Ratio Is Associated with Disability in Multiple Sclerosis: A Combined OCT and Subjective Visual Vertical Study.

Medicina (Kaunas, Lithuania)·2026
Same author

Down-sloping high-frequency audiometric findings in ENT-MS-12 auditory screen-positive patients with relapsing-remitting multiple sclerosis: A pilot case series.

Multiple sclerosis and related disorders·2026
Same author

Persistent postural-perceptual dizziness: subjective-objective dissociation and response to neurologist-led multimodal therapy.

Journal of neurology·2026
Same author

Non-verbal dichotic listening: A new cognitive hearing test for dementia.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Prospective Evaluation of the Neurology Same Day Emergency Care (NeuroSDEC) Model in Secondary Care: data from 931 patients over the first 12 months.

BMJ neurology open·2026
Same author

Cervical vestibular evoked myogenic potential asymmetry, but not amplitude, differentiates vestibular migraine during prolonged unidirectional visual motion.

Frontiers in neurology·2026
Same journal

Genome-wide spectrum of coding DNA variations in Indian patients with amyotrophic lateral sclerosis.

Journal of neurology·2026
Same journal

Number needed to treat and harm for lecanemab and donanemab in early Alzheimer disease.

Journal of neurology·2026
Same journal

Genetic spectrum and clinical features of PMP22 point mutations in Japanese Charcot-Marie-Tooth disease.

Journal of neurology·2026
Same journal

Migraine and auditory dysfunction: beyond comorbidity.

Journal of neurology·2026
Same journal

Efficacy and safety of ofatumumab in participants with relapsing multiple sclerosis and breakthrough disease on oral fingolimod or fumarates: results from the ARTIOS study.

Journal of neurology·2026
Same journal

Triple-crush mechanism in multiple sclerosis-associated trigeminal neuralgia.

Journal of neurology·2026
See all related articles

Related Experiment Video

Updated: Sep 8, 2025

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction
05:02

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction

Published on: August 30, 2019

7.3K

Rethinking positional nystagmus: beyond BPPV.

Amanda J Male1, George Korres2, Nehzat Koohi1

  • 1SENSE Research Unit, Department of Clinical and Movements Neurosciences, UCL Institute of Neurology, 33 Queen Square, London, WC1N 3BG, UK.

Journal of Neurology
|September 5, 2025
PubMed
Summary
This summary is machine-generated.

Positional nystagmus offers key insights into brain and vestibular function. A new approach is needed to better diagnose central positional nystagmus and improve dizziness management.

Keywords:
BPPVCentral positional nystagmusPositional dizzinessPositional nystagmus

More Related Videos

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform
10:12

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform

Published on: May 23, 2013

16.0K
Measuring the Influence of Magnetic Vestibular Stimulation on Nystagmus, Self-Motion Perception, and Cognitive Performance in a 7T MRT
08:57

Measuring the Influence of Magnetic Vestibular Stimulation on Nystagmus, Self-Motion Perception, and Cognitive Performance in a 7T MRT

Published on: March 3, 2023

2.0K

Related Experiment Videos

Last Updated: Sep 8, 2025

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction
05:02

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction

Published on: August 30, 2019

7.3K
Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform
10:12

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform

Published on: May 23, 2013

16.0K
Measuring the Influence of Magnetic Vestibular Stimulation on Nystagmus, Self-Motion Perception, and Cognitive Performance in a 7T MRT
08:57

Measuring the Influence of Magnetic Vestibular Stimulation on Nystagmus, Self-Motion Perception, and Cognitive Performance in a 7T MRT

Published on: March 3, 2023

2.0K

Area of Science:

  • Neurology
  • Neuroscience
  • Vestibular System

Background:

  • Positional nystagmus is a common clinical sign with significant diagnostic implications.
  • Current diagnostic approaches often misdiagnose positional nystagmus, favoring benign paroxysmal positional vertigo (BPPV) over central causes.
  • Over-reliance on imaging and underestimation of central positional nystagmus (CPN) hinder accurate diagnosis.

Purpose of the Study:

  • To advocate for a paradigm shift in diagnosing positional nystagmus.
  • To emphasize the importance of recognizing and interpreting CPN accurately.
  • To improve diagnostic accuracy and management strategies for dizziness.

Main Methods:

  • Review of current diagnostic frameworks for positional nystagmus.
  • Analysis of the diagnostic yield of clinical signs versus imaging.
  • Proposal for revised diagnostic criteria and educational emphasis.

Main Results:

  • The current framework inadequately addresses CPN, leading to diagnostic errors.
  • Clinical assessment of positional nystagmus provides crucial information often overlooked.
  • Objective diagnostic thresholds are currently lacking.

Conclusions:

  • A revised diagnostic approach is essential for positional nystagmus.
  • Strengthening neurological training in interpreting CPN is critical.
  • Accurate diagnosis of positional nystagmus improves patient outcomes for dizziness.