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Related Experiment Videos

[Mitral prolapse and sudden deafness].

H Moulonguet, L M Gougelot

    Annales D'Oto-Laryngologie Et De Chirurgie Cervico Faciale : Bulletin De La Societe D'Oto-Laryngologie Des Hopitaux De Paris
    |January 1, 1985
    PubMed
    Summary

    Sudden deafness may be caused by an embolic process, not just vascular spasm. Barlow's disease, a mitral valve abnormality, is frequently linked to this condition, suggesting new treatment approaches.

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    Area of Science:

    • Cardiology
    • Neurology
    • Ophthalmology

    Context:

    • Sudden idiopathic sudden deafness is often attributed to vascular spasm, though this remains unproven.
    • An embolic process is proposed as a frequent alternative explanation for sudden deafness.
    • Barlow's disease, a mitral valve abnormality, is increasingly recognized as a potential cause.

    Purpose:

    • To investigate the role of Barlow's disease in sudden idiopathic sudden deafness.
    • To challenge the traditional vascular spasm hypothesis.
    • To propose alternative therapeutic strategies based on the identified etiology.

    Summary:

    • A study of 58 sudden deafness cases found Barlow's disease in 39.6%, significantly higher than the general population (5-10%).
    • Barlow's disease, detectable via echocardiography, is a known cause of embolic events in cerebral and retinal circulation.
    • This finding suggests replacing vasodilator therapy with anticoagulants like heparin and antiplatelet agents for sudden deafness.

    Impact:

    • Highlights Barlow's disease as a significant, often overlooked cause of sudden deafness.
    • Recommends echocardiography for diagnosing potential embolic sources in sudden deafness patients.
    • Suggests a shift in treatment paradigms from vasodilators to anticoagulation and antiplatelet therapies.

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