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Updated: Jun 24, 2026
Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
Published on: January 6, 2011
Awake surgery with direct electrical stimulation for safe resection of a deep posterior thalamic cavernous
Benoit Simonet1, Lydiane Mondot2, Fabien Almairac3
1Neurosurgery Department, Pasteur 2 Hospital, University Hospital of Nice, France.
Background:
Treating symptomatic deep-seated cerebral cavernous malformations (CCMs) is challenging due to surgical risks.
Case Description:
A 37-year-old man underwent awake craniotomy with direct electrical stimulation (DES) for excision of a left posterior thalamic CCM. A transcortical transventricular approach through the superior parietal lobe enabled safe navigation around critical associative and projection white matter tracts.
Results:
Postoperative MRI confirmed complete resection with preservation of major tracts, and the patient showed significant recovery at three months.
Conclusion:
This case highlights the potential of awake surgery with DES as a safe and effective method for deep-seated CCMs traditionally deemed inoperable.
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