Related Experiment Video
Updated: Jan 18, 2026

Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy
Published on: September 29, 2016
Which came first - the messenger, the activator, or the receiver?
Amalie Scheel Tost1, Frederik Grønbæk Tidemand1, Anja Thoe Fuglsang1
1Department of Plant and Environmental Sciences, Section of Transport Biology, University of Copenhagen, Thorvaldsensvej 40, 1871 Frederiksberg C, Denmark.
Abstract:
Plants have developed sophisticated signaling mechanisms to adapt to environmental changes, and secreted peptides play crucial roles. Sulfated tyrosine (sTyr) peptides are important regulators of plant growth, nutrient uptake, defense responses, and seed development. This study delves into the evolution of sTyr peptides, their receptors, and the enzyme tyrosylprotein sulfotransferase (TPST) that is responsible for their activation. By exploring the evolutionary timeline of sTyr peptide function, we aim to determine their significance in the emergence of land plants. We map the distribution of sTyr peptides, their receptors, and TPST across different plant species, and identify key sites essential for their activity. These findings provide a comprehensive overview of the functional and evolutionary significance of sTyr peptidesand offer insights into their potential agricultural applications.
More Related Videos
08:00Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
Published on: October 4, 2024
09:32Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
Published on: June 15, 2017
Related Concept Videos
Intracellular Signaling Cascades
Amplifying Signals via Second Messengers
Cell-surface Signaling
Interactions Between Signaling Pathways
Convergence and divergence, and cross-talk between signaling pathways
Two distinct signaling pathways can converge on a single functional unit, which may either be a single protein or a complex of proteins. The response is either functionally distinct or synergistic between the two pathways but different from the response...
Chemical Signaling in the Endocrine System
Lipid-soluble hormones, such as steroid hormones, demonstrate an intracellular action. These hormones traverse cell membranes due to their lipid nature. Once inside the target cell, they...
Signal Transduction: Overview
Typically, signal transduction involves three...