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Updated: Jan 18, 2026

Real Time Detection of In Vitro Tumor Cell Apoptosis Induced by CD8+ T Cells to Study Immune Suppressive Functions of Tumor-infiltrating Myeloid Cells
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[A coupled diffusion-based model of interaction between tumor metastasis and myeloid-derived suppressive cells]

Yating Huang1, Zhenyou Wang1

  • 1School of Mathematics and Statistics, Guangdong University of Technology, Guangzhou 510520, China.

Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University
|September 8, 2025
PubMed
Summary

Mathematical modeling reveals myeloid-derived suppressive cells (MDSCs) are crucial in the pre-metastatic niche (PMN). These cells significantly influence tumor metastasis, particularly angiogenesis and immune suppression, offering insights for cancer treatment strategies.

Keywords:
coupled diffusionexistence uniquenesspartial differentiationsuppressive cellstumor metastasis

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