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A Rare Presentation of Acute Generalized Exanthematous Pustulosis With Refractory Shock
Maria C Perez-Mitchell1, Mariela Ginés-Rosario2, Ricardo Fernandez-Gonzalez1
1Pulmonary and Critical Care Medicine, San Juan City Hospital, San Juan, PRI.
Acute generalized exanthematous pustulosis (AGEP) can cause severe skin reactions. This case highlights an uncommon AGEP presentation leading to circulatory shock and acute kidney injury in a middle-aged woman.
Area of Science:
- Dermatology
- Nephrology
- Critical Care Medicine
Background:
- Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction characterized by pustular lesions, fever, and neutrophilia, typically occurring 24-48 hours after a trigger.
- While AGEP usually involves only skin manifestations, rare cases can present with systemic complications.
- The condition commonly affects female patients and typically resolves within 1-2 weeks after discontinuing the causative agent.
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