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Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

484
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
484
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

963
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
963
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

472
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
472

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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
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Obstructive Sleep Apnea in Idiopathic Intracranial Hypertension: Systematic Review and Meta-Analysis.

Mohammad Karam1,2, Abdulmalik Alsaif3,4, Dalal Alroumi2

  • 1Department of Ophthalmology and Visual Sciences, McGill University Health Center, Montreal, Canada.

Neuro-Ophthalmology (Aeolus Press)
|September 8, 2025
PubMed
Summary

Obstructive sleep apnea (OSA) is significantly associated with idiopathic intracranial hypertension (IIH). Nearly 42% of IIH patients have OSA, warranting screening for this common sleep disorder.

Keywords:
Obstructive sleep apneadiagnosisidiopathic intracranial hypertensionprevalencescreening

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Area of Science:

  • Neurology
  • Pulmonology
  • Ophthalmology

Background:

  • Idiopathic intracranial hypertension (IIH) is a neurological disorder characterized by increased intracranial pressure without a clear cause.
  • Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder with potential systemic health implications.
  • The relationship between OSA and IIH requires further investigation to inform clinical practice.

Purpose of the Study:

  • To systematically review and meta-analyze the existing literature on the association between obstructive sleep apnea (OSA) and idiopathic intracranial hypertension (IIH).
  • To determine the pooled prevalence of OSA in patients diagnosed with IIH.

Main Methods:

  • A systematic review and meta-analysis were conducted following PRISMA guidelines.
  • Searches were performed in MEDLINE, EMBASE, and Cochrane Library databases.
  • Eight studies involving 241 patients were included in the final analysis.

Main Results:

  • The overall pooled prevalence of OSA in patients with IIH was 42.4% (95% CI: 0.258 to 0.609), indicating a significant association (p < .05).
  • Subgroup analysis showed a prevalence of 40.7% for confirmed OSA diagnoses and 46.4% for positive OSA screenings.
  • The findings suggest a robust link between these two conditions.

Conclusions:

  • A significant proportion of patients with newly diagnosed IIH also have OSA.
  • Clinicians should consider screening patients with IIH for OSA to facilitate timely diagnosis and management.
  • Further research may explore the pathophysiological mechanisms linking OSA and IIH.