Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sarin Adsorption and Decomposition on Semiwet Surfaces: Density Functional Theory Insight.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Interfacial Electron Transfer in Self-Assembled Arylated Gold Nanoparticles-Ferrocenium Organometallics.

Inorganic chemistry·2026
Same author

Nanomaterial Enhanced PVDF Mixed Matrix Membranes for Microfluidic Electrochemical Desalination.

Membranes·2026
Same author

Investigating soil and ATCC bacterial strains for their ability to synthesize anisotropic gold nanoparticles.

Applied microbiology and biotechnology·2026
Same author

Alginate-tungsten trioxide-reduced graphene-based membranes for PEM fuel cells operating above the boiling point of water.

RSC advances·2025
Same author

Characterizations of Electrospun PVDF-Based Mixed Matrix Membranes with Nanomaterial Additives.

Nanomaterials (Basel, Switzerland)·2025

Related Experiment Video

Updated: Jan 18, 2026

Asymmetrical Flow Field-Flow Fractionation for Sizing of Gold Nanoparticles in Suspension
09:33

Asymmetrical Flow Field-Flow Fractionation for Sizing of Gold Nanoparticles in Suspension

Published on: September 11, 2020

6.7K

Rational Design and Applications of Ultrasmall Gold Nanoparticles.

Javad B M Parambath1,2,3, Mahreen Arooj4, Kabali Vijai Anand2

  • 1Center for Advanced Materials Research, Research Institute of Sciences and Engineering, University of Sharjah, 27272, Sharjah, United Arab Emirates.

Topics in Current Chemistry (Cham)
|September 8, 2025
PubMed
Summary
This summary is machine-generated.

Controlling gold nanoparticle size is crucial for various applications. Ultrasmall gold nanoparticles (uAuNPs) and gold nanoclusters (AuNCs) have distinct properties, requiring careful synthesis and stabilization for optimal performance.

Keywords:
ApplicationsCalculationsGold nanoparticlesNanoclustersSynthesisUltrasmall

More Related Videos

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery
10:38

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery

Published on: January 15, 2018

13.0K
A Simple Method for the Size Controlled Synthesis of Stable Oligomeric Clusters of Gold Nanoparticles under Ambient Conditions
08:21

A Simple Method for the Size Controlled Synthesis of Stable Oligomeric Clusters of Gold Nanoparticles under Ambient Conditions

Published on: February 5, 2016

22.6K

Related Experiment Videos

Last Updated: Jan 18, 2026

Asymmetrical Flow Field-Flow Fractionation for Sizing of Gold Nanoparticles in Suspension
09:33

Asymmetrical Flow Field-Flow Fractionation for Sizing of Gold Nanoparticles in Suspension

Published on: September 11, 2020

6.7K
Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery
10:38

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery

Published on: January 15, 2018

13.0K
A Simple Method for the Size Controlled Synthesis of Stable Oligomeric Clusters of Gold Nanoparticles under Ambient Conditions
08:21

A Simple Method for the Size Controlled Synthesis of Stable Oligomeric Clusters of Gold Nanoparticles under Ambient Conditions

Published on: February 5, 2016

22.6K

Area of Science:

  • Nanotechnology and Materials Science
  • Chemical Engineering
  • Biomedical Engineering

Background:

  • Controlling gold nanoparticle (AuNP) size is critical for applications in diagnostics, sensing, therapy, and environmental remediation.
  • Ultrasmall gold nanoparticles (uAuNPs, 2-5 nm) and gold nanoclusters (AuNCs, <2 nm) exhibit distinct properties but are often conflated in literature.
  • Their unique optoelectronic properties differ significantly from bulk gold and larger nanoparticles, driven by quantum effects.

Purpose of the Study:

  • To review the synthesis, medical, and environmental applications of ultrasmall gold nanoparticles (uAuNPs).
  • To differentiate the properties and applications of uAuNPs and gold nanoclusters (AuNCs).
  • To highlight the importance of size control and ligand stabilization for uAuNP and AuNC performance.

Main Methods:

  • Literature review focusing on synthesis strategies, medical and environmental applications, and computational studies of uAuNPs.
  • Discussion of methods to prevent aggregation, such as nucleation within porous materials.
  • Analysis of ligand stabilization techniques for uAuNPs and AuNCs.

Main Results:

  • Distinct chemical, physical, and optoelectronic properties arise from the quantum size effects in uAuNPs and AuNCs.
  • Synthesis often yields both uAuNPs and AuNCs simultaneously, necessitating separation.
  • Ligand choice significantly impacts stabilization, with soft ligands like phosphine and thiolate common for AuNCs, while uAuNPs allow broader ligand sets.

Conclusions:

  • Precise control over uAuNP and AuNC size is essential for tailoring their unique properties and enhancing performance in diverse applications.
  • Understanding the differences between uAuNPs and AuNCs is vital for targeted development in healthcare and environmental sectors.
  • Computational studies reveal that tuning the HOMO-LUMO energy gap, linked to the gold atom count, is key to optimizing nanoparticle function.