Echocardiographic findings in young adults with primary hypertension: A scoping review protocol

Lyana Shahirah Mohamad Yamin1,2, Maryam Alsharqi3, Mohd Asyiq Al-Fard Mohd Raffali4

  • 1Centre for Diagnostic, Therapeutic and Investigative Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

Plos One
|September 8, 2025
PubMed

Insights

This scoping review protocol examines echocardiography for early detection of cardiac changes in young adults (18-39) with primary hypertension. It addresses a gap in understanding hypertension

Area of Science:

  • Cardiology
  • Medical Imaging

Background:

  • Primary hypertension significantly impacts cardiac structure and function.
  • Existing research on cardiac effects of hypertension predominantly focuses on older adults, neglecting young adults.
  • A knowledge gap exists regarding early cardiac changes in young adults with primary hypertension.

Purpose of the Study:

  • To assess conventional and advanced echocardiographic parameters for early detection of cardiac changes in young adults (18-39) with primary hypertension.
  • To identify left ventricular geometric patterns associated with primary hypertension in this demographic.
  • To lay the groundwork for future research on the diagnostic and prognostic significance of echocardiographic findings.

Main Methods:

  • Systematic literature search across major databases (MEDLINE, EMBASE, Web of Science, Scopus, Cochrane Central).
  • Scoping review methodology to outline reported echocardiographic findings, parameters, and identified abnormalities.
  • Focus on studies involving young adults aged 18-39 with primary hypertension.

Main Results:

  • This section will be populated upon completion of the review.
  • The review will synthesize current evidence on echocardiographic findings in young adults with primary hypertension.
  • It will detail conventional parameters, left ventricular geometry, and advanced echocardiographic techniques used.

Conclusions:

  • Echocardiography holds potential for early detection of cardiac alterations in young adults with primary hypertension.
  • Further research is needed to establish the diagnostic and prognostic value of specific echocardiographic findings.
  • This review will guide future studies and clinical practice for risk assessment in this population.

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