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Updated: Jan 18, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
[A case of lung poorly differentiated squamous cell carcinoma-associated retinopathy]
1Department of Ocular Fundus, The First People's Hospital of Xianyang, Xianyang 712000, China.
Abstract:
A 65-year-old male patient presented with "blurred vision in the right eye for 1 week". At the first visit, the best corrected visual acuity (BCVA) of both eyes was 0.8, no obvious abnormalities were observed in fundus examination, and optical coherence tomography (OCT) revealed the loss of outer retinal layers adjacent to the macula in the right eye. Ten days after the initial visit, the visual acuity of both eyes declined. OCT showed loss of outer retinal layers in both eyes except for the macular area, accompanied by short-term visual acuity decrease and binocular visual field defects. Electroretinography (ERG) demonstrated decreased amplitudes of a-waves and b-waves in both eyes under light and dark adaptation. Combined with imaging findings of lung squamous cell carcinoma and positive anti-recoverin antibody, the clinical diagnosis was lung squamous cell carcinoma-associated retinopathy.

