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Comprehensive study on selenium- and zinc-enriched duck embryo egg powder: component analysis, safety evaluation and
Pengkui Xia1,2, Ruyang Wang2, Dandan Ruan1
1Key Laboratory of Egg Processing, Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan, China.
Journal of the Science of Food and Agriculture
|September 9, 2025
Summary
Selenium and zinc-enriched duck embryo egg (SZDE) powder is safe and effectively reduces inflammation in rats with prostatitis. This dietary supplement may offer a new strategy for improving prostate health.
Area of Science:
- Nutritional Science
- Immunology
- Reproductive Biology
Background:
- Selenium and zinc are vital for immune function and reproductive health.
- These elements have demonstrated potential in managing prostatitis and modulating reproductive performance.
- Duck embryo egg (SZDE) powder is rich in selenium and zinc.
Purpose of the Study:
- Analyze the composition of SZDE, focusing on trace elements and oligopeptides.
- Evaluate the acute toxicity of SZDE.
- Investigate the anti-inflammatory effects of SZDE in a rat model of prostatitis.
Main Methods:
- Compositional analysis of SZDE.
- Acute toxicity testing in male and female mice.
- Construction of a prostatitis rat model.
- Assessment of inflammatory markers, androgen levels, and the MAPK/p38 pathway.
Main Results:
- SZDE exhibited significantly higher levels of selenium and zinc compared to normal eggs.
- SZDE demonstrated no observable toxicity in mice.
- SZDE intervention led to reduced pro-inflammatory cytokines and increased androgen levels (P < 0.05).
- SZDE treatment significantly improved prostatitis by inhibiting the MAPK/p38 pathway (P < 0.05).
Conclusions:
- SZDE is safe for consumption.
- SZDE possesses significant prostatitis-regulating effects.
- SZDE may represent a novel dietary approach for maintaining prostate health.
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