Minimally Invasive Facial Lifting Using the Versatility of Calcium Hydroxyapatite (STIIM)

Facial aging is a multifactorial process characterized by skin laxity, volume loss, and collagen degradation. Calcium Hydroxyapatite (CaHA) is a versatile biostimulatory filler that can provide both structural support and collagen stimulation. This study evaluates a novel technique using CaHA with tailored dilutions for minimally invasive facial rejuvenation, focusing on key ligamentous structures.

To assess the aesthetic outcomes, patient satisfaction, and safety profile of the technique using regionalized CaHA dilutions.

A prospective, single-center study was conducted involving 20 subjects with facial laxity. CaHA injections were performed using three distinct dilution ratios protocols, targeting the zygomatic, temporal, and mandibular regions. Endpoints were evaluated through Face-Q questionnaires, GAIS, and standardized 2D and 3D imaging.

At 90 days, 94% of subjects reported aesthetic improvement, and the mean Face-Q Skin score increased from 43.2 ± 14.7 to 74.9 ± 14.7. These results were maintained at 360 days, with 94% of participants continuing to report improvement and a sustained FACE-Q Skin score of 77.2 ± 16.4. Investigator assessments confirmed long-term improvements, and 3D imaging showed persistent enhancement in facial contours. Adverse events were mild and self-limiting.

This CaHA-based technique offers a safe, minimally invasive facial lifting effect with sustained improvement over 12 months. Its effectiveness is enhanced by targeting facial ligaments and customizing dilution based on anatomical region.