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4D Lips Technique Based on Anatomy for Naturalization.

Melina Kichler1, Marta Barros1, Carolina de Freitas1

  • 1From the Independent Researcher, São Paulo, Brazil.

Plastic and Reconstructive Surgery. Global Open
|January 19, 2026
PubMed
Summary

The 4D Lips technique offers a safe and effective method for lip augmentation, achieving natural-looking results and high patient satisfaction through an anatomy-based approach. This hyaluronic acid filler technique prioritizes dimension, distribution, dynamics, and patient desire for personalized outcomes.

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Area of Science:

  • Aesthetic Medicine
  • Dermatology
  • Plastic Surgery

Background:

  • Lip augmentation is a popular aesthetic procedure, especially among younger demographics.
  • Achieving natural-looking results requires a precise, anatomy-based approach to minimize complications.
  • The 4D Lips technique, utilizing multiphasic hyaluronic acid fillers, aims to enhance lip shape while respecting anatomical landmarks.

Purpose of the Study:

  • To introduce and evaluate the 4D Lips technique for lip augmentation.
  • To assess patient satisfaction and safety outcomes of the novel technique.
  • To demonstrate the efficacy of an anatomy-informed, personalized approach to lip enhancement.

Main Methods:

  • The study involved ten female patients undergoing lip augmentation with the 4D Lips technique.
  • A combination of subtechniques, including tubercle marking, vertical elongation, and vermilion border eversion, was employed.
  • Two hyaluronic acid fillers with different viscoelastic properties (medium G' for structure, low G' for contour) were used.

Main Results:

  • All patients reported high satisfaction with the natural appearance of their lips post-procedure.
  • Mild, transient side effects like swelling were observed and resolved without intervention.
  • The anatomy-based technique facilitated precise volumization, refined contouring, and maintained natural lip dynamics without major complications.

Conclusions:

  • The 4D Lips technique provides a safe and effective method for lip augmentation, yielding high patient satisfaction.
  • An anatomy-informed and personalized approach is crucial for achieving harmonious and individualized lip enhancement outcomes.
  • Further research with larger sample sizes and long-term follow-up is recommended to validate these findings.