Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Case Studies01:22

Case Studies

13.3K
There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.
13.3K
Introspection01:29

Introspection

210
Introspection, long upheld as a reliable route to self-knowledge, involves examining one's thoughts, emotions, and mental processes. It underpins many psychological practices, from mindfulness meditation to psychotherapy and self-help strategies. However, empirical evidence challenges the accuracy of introspection as a means of understanding oneself.Limitations of Introspective InsightSeminal work by Nisbett and Wilson demonstrated that individuals are frequently unaware of the true causes...
210
Cognitive Learning01:21

Cognitive Learning

1.0K
Cognitive learning is based on purposive behavior, incidental learning, and insight learning.
E. C. Tolman's theory of purposive behavior emphasizes that much behavior is goal-directed. He argued that to understand behavior, we must look at the entire sequence of actions leading to a goal. For instance, high school students study hard, not just due to past reinforcement but also to achieve the goal of getting into a good college.
Tolman introduced the idea that behavior is influenced by...
1.0K
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models01:06

Model Approaches for Pharmacokinetic Data: Distributed Parameter Models

243
Pharmacokinetic models are mathematical constructs that represent and predict the time course of drug concentrations in the body, providing meaningful pharmacokinetic parameters. These models are categorized into compartment, physiological, and distributed parameter models.
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
243
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

682
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
682
Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis00:59

Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis

322
Noncompartmental analyses offer an alternative method for describing drug pharmacokinetics without relying on a specific compartmental model. In this approach, the drug's pharmacokinetics are assumed to be linear, with the terminal phase log-linear. This assumption allows for simplified analysis and interpretation of the drug's behavior in the body.
One important characteristic of noncompartmental analyses is that drug exposure increases proportionally with increasing doses. This...
322

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inhalation airflow and ventilation efficiency in subject-specific human upper airways.

Respiratory physiology & neurobiology·2020
Same author

Adverse Effects of Low-Dose Methotrexate in a Randomized Double-Blind Placebo-Controlled Trial: Adjudicated Hematologic and Skin Cancer Outcomes in the Cardiovascular Inflammation Reduction Trial.

ACR open rheumatology·2020
Same author

Preparation and <i>in Vitro</i> Antitumor Study of Two-Dimensional Muscovite Nanosheets.

Langmuir : the ACS journal of surfaces and colloids·2020
Same author

Identification and Bioinformatic Assessment of circRNA Expression After <i>RMI1</i> Knockdown and Ionizing Radiation Exposure.

DNA and cell biology·2020
Same author

Pollution haven or halo? The role of the energy transition in the impact of FDI on SO2 emissions.

The Science of the total environment·2020
Same author

Efficacy and Safety of Bevacizumab Plus Oxaliplatin- or Irinotecan-Based Doublet Backbone Chemotherapy as the First-Line Treatment of Metastatic Colorectal Cancer: A Systematic Review and Meta-analysis.

Drug safety·2020
Same journal

HardFlow: Hard-Constrained Sampling for Flow-Matching Models Via Trajectory Optimization.

IEEE transactions on pattern analysis and machine intelligence·2026
Same journal

Industrial Brain: Self-Evolving Neuro-Symbolic Autonomy with Causal Resilience for Cyber-Physical Systems.

IEEE transactions on pattern analysis and machine intelligence·2026
Same journal

Adaptive Hardness-Driven Dictionary Distillation for Incomplete Streaming View Clustering.

IEEE transactions on pattern analysis and machine intelligence·2026
Same journal

Mixture of Global and Local Experts with Diffusion Transformer for Controllable Face Generation.

IEEE transactions on pattern analysis and machine intelligence·2026
Same journal

Task-KV: Task-aware KV Cache Optimization via Semantic Differentiation of Attention Heads.

IEEE transactions on pattern analysis and machine intelligence·2026
Same journal

Achieving Text-based Person Retrieval with Any Granularity.

IEEE transactions on pattern analysis and machine intelligence·2026
See all related articles

Related Experiment Video

Updated: Jan 18, 2026

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering
09:43

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering

Published on: November 22, 2019

6.7K

Toward Effective Knowledge Distillation: Navigating Beyond Small-Data Pitfall.

Zhiwei Hao, Jianyuan Guo, Kai Han

    IEEE Transactions on Pattern Analysis and Machine Intelligence
    |September 9, 2025
    PubMed
    Summary
    This summary is machine-generated.

    Knowledge distillation (KD) methods often fail on large datasets due to a "small-data pitfall." Effective KD requires incorporating more information, not just modifying loss functions, for consistent performance across data scales.

    More Related Videos

    Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
    05:47

    Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

    Published on: June 13, 2025

    1.3K
    Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
    10:41

    Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

    Published on: May 9, 2017

    9.6K

    Related Experiment Videos

    Last Updated: Jan 18, 2026

    Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering
    09:43

    Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering

    Published on: November 22, 2019

    6.7K
    Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
    05:47

    Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

    Published on: June 13, 2025

    1.3K
    Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
    10:41

    Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

    Published on: May 9, 2017

    9.6K

    Area of Science:

    • Artificial Intelligence
    • Machine Learning
    • Deep Learning

    Background:

    • Large models trained on extensive datasets show exceptional performance.
    • Knowledge Distillation (KD) is used to create compact models for edge devices.
    • Existing KD methods may not scale effectively with larger datasets and models.

    Purpose of the Study:

    • To investigate the effectiveness of current KD methods on large-scale datasets.
    • To identify limitations and guide the development of more robust KD techniques.
    • To address the "small-data pitfall" in knowledge distillation.

    Main Methods:

    • Revisiting and evaluating current KD approaches on large-scale datasets.
    • Analyzing the knowledge transfer process in KD.
    • Proposing and evaluating a new KD method combining vanilla KD with deep supervision.

    Main Results:

    • Most KD modifications are ineffective on large datasets, exhibiting a "small-data pitfall."
    • Incorporating more information into the student model is crucial for effective KD.
    • The proposed method combining KD with deep supervision significantly outperforms existing methods.

    Conclusions:

    • The effectiveness of KD methods is highly dependent on the scale of the dataset.
    • Focusing on enhancing information transfer is more critical than altering loss functions for KD.
    • The study provides insights for developing consistently effective KD methods for large-scale applications.