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Super-resolution Fluorescence Microscopy

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...

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Related Experiment Video

Updated: Jan 18, 2026

High-resolution Imaging of Nuclear Dynamics in Live Cells under Uniaxial Tensile Strain

High-resolution Imaging of Nuclear Dynamics in Live Cells under Uniaxial Tensile Strain

Published on: June 2, 2019

Frustration under the microscope

Nicolas Bergeal¹

¹Laboratoire de Physique et d'Étude des Matériaux, ESPCI Paris, Université PSL, CNRS, Sorbonne Université, Paris, France. nicolas.bergeal@espci.fr.

Nature Materials

|September 9, 2025

Summary

No abstract available in PubMed .

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