Related Experiment Video
Updated: Jul 10, 2026

07:43
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
19.5K
[Submental swelling in an Ethiopian man]
L S Klunder1, M S Louwe1, A Vissink1
1the Department of Oral and Maxillofacial Surgery, University Medical Center Groningen (UMCG).
Nederlands Tijdschrift Voor Tandheelkunde
|September 10, 2025
Summary
A 27-year-old Ethiopian man developed a submental swelling after a molar extraction. Diagnosis confirmed extrapulmonary lymphogenous tuberculosis, highlighting the head and neck region as a common site for this infection.
Area of Science:
- Medicine
- Infectious Diseases
- Oral and Maxillofacial Surgery
Background:
- Tuberculosis (TB) is a significant global health concern.
- Extrapulmonary TB can present with diverse clinical manifestations.
- Head and neck lymphadenopathy is a common presentation of extrapulmonary TB.
Purpose of the Study:
- To report a rare case of extrapulmonary lymphogenous tuberculosis presenting as a submental swelling.
- To emphasize the importance of considering TB in the differential diagnosis of neck masses, even after dental procedures.
Main Methods:
- Clinical examination of a patient with a submental swelling.
- Intraoral examination of dentition.
- Microbiological examination including polymerase chain reaction (PCR) for Mycobacterium tuberculosis.
- Radiological assessment (chest X-ray).
Main Results:
- A 27-year-old man presented with a tender, firm submental swelling with central ulceration post-molar extraction.
- Systemic symptoms including fatigue, weight loss, night sweats, fever, headache, and cough were noted.
- PCR confirmed Mycobacterium tuberculosis, leading to a diagnosis of extrapulmonary lymphogenous tuberculosis.
- Chest X-rays were unremarkable.
Conclusions:
- Extrapulmonary lymphogenous tuberculosis should be considered in the differential diagnosis of submental swellings, particularly in endemic areas or in patients with relevant travel history.
- Early microbiological diagnosis is crucial for effective management of TB.
- The head and neck region represents the most frequent site for extrapulmonary tuberculosis.
Related Concept Videos
Increased Intracranial Pressure ll: Pathophysiology
Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Cerebral Edema l: Introduction
Cerebral edema is a pathological increase in brain water content that disrupts intracranial pressure regulation and impairs neurological function. Because the cranial vault is rigid, even modest increases in tissue volume can compromise cerebral perfusion, distort neural structures, and initiate secondary injury. Cerebral edema develops through four principal mechanisms: vasogenic, cytotoxic, interstitial, and ionic.Vasogenic EdemaVasogenic edema arises from disruption of the blood–brain...

