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Updated: Jul 27, 2026

A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells
Published on: May 6, 2018
Molecular Morphology of Telangiectatic Osteosarcoma Associated With Сystic Content: A Case Report
David Makaridze1, Armaz Mariamidze2, Tamuna Gvianishvili3
1Histology and Embryology, David Tvildiani Medical University, Tbilisi, GEO.
Abstract:
This case report is focused on a patient (a 32-year-old previously healthy man) with a femoral bone tissue tumor. The case underscores the diagnostic complexity of Telangiectatic Osteosarcoma (TOS) with Aneurysmal Bone Cystic (ABC) lesion and the importance of maintaining special immunohistochemical markers for differential diagnosis between low-grade osteosarcoma, primary ABC, and suspected TOS, which is a true mimicker of ABC. On the other hand, this presentation describes some molecular rearrangements seen in ABC.
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