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Exploring The Utility Of Fdg Pet-ct In Metastatic Recurrent Extra Skeletal Renal Osteosarcoma.

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Exploring The Utility Of Fdg Pet-ct In Metastatic Recurrent Extra Skeletal Renal Osteosarcoma.

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Exploring the Utility of FDG PET-CT in Metastatic Recurrent Extra Skeletal Renal Osteosarcoma.

John Pathak¹, Dikhra Khan¹, Shamim Ahmed Shamim¹

¹Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

Indian Journal of Nuclear Medicine : IJNM : the Official Journal of the Society of Nuclear Medicine, India

|September 10, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

Metastatic renal osteosarcoma is rare. This case shows 18-fluorine-fluorodeoxyglucose (FDG) PET/CT effectively detecting metastatic renal osteosarcoma and its recurrence, aiding treatment response assessment.

Keywords:

Extraosseous fluorodeoxyglucose positron emission tomography/computed tomography osteosarcoma recurrence renal

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Area of Science:

Oncology
Radiology
Nuclear Medicine

Background:

Metastatic renal osteosarcoma is an exceptionally rare clinical diagnosis.
Extraskeletal osteosarcoma, particularly originating from the kidney, presents unique diagnostic and management challenges.

Purpose of the Study:

To report a rare case of metastatic renal osteosarcoma.
To highlight the utility of 18-fluorine-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in diagnosing, monitoring treatment response, and detecting recurrence of extraskeletal osteosarcoma.

Main Methods:

Case presentation of a 52-year-old male post-nephrectomy.
Utilized 18F-FDG PET/CT for initial staging and follow-up assessments.
Administered carboplatin and doxorubicin chemotherapy.

Main Results:

Initial 18F-FDG PET/CT revealed avid lesions in the renal bed with hepatic extension.
Favorable response to chemotherapy with resolution of FDG-avid lesions post-treatment.
Recurrence detected at 6 months with local invasion and liver metastasis.

Conclusions:

18F-FDG PET/CT is a valuable tool for evaluating metastatic renal osteosarcoma.
This imaging modality aids in assessing chemotherapy response and detecting early recurrence.
The case underscores the importance of vigilant follow-up for extraskeletal osteosarcoma.