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Updated: May 5, 2026

Intravenous Injections in Neonatal Mice
Published on: November 11, 2014
Ivermectin toxicosis in a foal: Use of intravenous lipid emulsion therapy
Shannon Darby1, SallyAnne DeNotta1, Diego E Gomez1
1Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, Gainesville, Florida 32608, USA (Darby, DeNotta, Gomez); Abu Dhabi Equine and Camel Hospital, Al Wathba, Abu Dhabi, United Arab Emirates (Gomez).
Abstract:
This report describes a case of ivermectin toxicosis in a 4-day-old thoroughbred colt successfully treated with intravenous lipid emulsion (ILE) without complications. This case supports the use of ILE as a safe and effective therapy for the management of lipophilic drug toxicosis in foals. Key clinical message: Ivermectin toxicosis, though rare in equine neonates, can occur following accidental overdose and induces severe neurologic signs. In this case, ILE administration resulted in rapid neurologic improvement and complete recovery without adverse effects, supporting its use as a safe and effective antidote for lipophilic drug toxicosis in foals.
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