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Unraveling the Pertussis Outbreak in Mexico: Insights from a Multicenter 2024-2025 Study
Marisol Silva Dirzo1, José Iván Castillo Bejarano2, María Citlalli Casillas Casillas3
1From the Department of Pediatrics Infectious Diseases, Hospital del Niño Morelense, Cuernavaca.
None:
We analyzed 59 pediatric pertussis cases during Mexico's 2024-2025 outbreak. Mortality was 13.6%, with low maternal Tdap coverage (27.1%) and incomplete infant vaccination (16.9%). Mortality correlated with intensive care unit admission, intubation, leukocytosis and coronavirus codetection. Peak leukocyte count predicted mortality ( P = 0.027; area under the curve = 0.79). Findings underscore the need for maternal immunization and early detection.
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