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Transition of patients with hereditary nephropathies from paediatric to adult care

Maria Vanessa Perez Gomez1,2,3, George-Claudiu Costea4, Laura Claus5

  • 1Department of Nephrology and Hypertension, Health Research Institute-Fundación Jiménez Díaz University Hospital, Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
|September 10, 2025
PubMed

Insights

Transitioning adolescents and young adults with chronic kidney disease (CKD) to adult care requires careful planning. This guidance offers practical advice for healthcare professionals to ensure better outcomes for young CKD patients.

Area of Science:

  • Nephrology
  • Pediatric Nephrology
  • Genetics

Background:

  • Adolescents and young adults with chronic kidney disease (CKD), especially those with genetic kidney diseases, face complex challenges during the transition from pediatric to adult care.
  • This transition involves changes in healthcare providers and significant developmental, psychosocial, and medical issues.

Purpose of the Study:

  • To develop practical advice for healthcare professionals managing the transition of young CKD patients to adult nephrology care.
  • To provide key principles and recommendations for a successful transition process, focusing on early planning, patient education, and multidisciplinary coordination.

Main Methods:

  • Collaboration between the ERA Working Group on Genes and Kidney and the ESPN Working Group on Inherited Kidney Diseases.
  • Development of practical recommendations and identification of knowledge gaps for improving transition care.

Main Results:

  • Outlines key principles for successful transition, emphasizing early planning, patient education, individualized care, and multidisciplinary coordination.
  • Highlights special considerations for genetic kidney diseases, including syndromic aspects and reproductive health.
  • Identifies knowledge gaps and proposes future research directions.

Conclusions:

  • Harmonizing practices and fostering shared responsibility between pediatric and adult nephrology teams can improve health outcomes.
  • The initiative aims to enhance patient empowerment and long-term engagement in care for young people with CKD.
  • Encourages implementation of adapted transition protocols within national and local healthcare systems.

Keywords:
chronic kidney diseasegenetic kidney diseaseinherited kidney diseasetransfertransition

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