COMPARING THE PREDICTIVE EFFICACY OF MELD AND ALBI SCORES IN LIVER CIRRHOSIS PATIENTS WITH ACUTE UPPER...

Area of Science:

• Hepatology
• Gastroenterology
• Critical Care Medicine

Background:

• Acute upper gastrointestinal bleeding (AUGIB) is a life-threatening emergency, particularly in patients with liver cirrhosis.
• Liver cirrhosis significantly increases morbidity and mortality associated with AUGIB.

Purpose of the Study:

• To evaluate the predictive accuracy of the Albumin-to-Bilirubin (ALBI) ratio and Model for End-Stage Liver Disease (MELD) scores for short-term outcomes in patients with AUGIB and liver cirrhosis.
• To compare the prognostic capabilities of ALBI and MELD scores in this patient population.

Main Methods:

• A retrospective study of 102 patients admitted with AUGIB and liver cirrhosis.
• Assessment of clinical data, laboratory results (including ALBI and MELD scores), and patient outcomes (in-hospital mortality, rebleeding, 1-month mortality).
• Statistical comparison of ALBI and MELD scores in predicting key adverse events.

Main Results:

• The overall survival rate was 68.5%.
• Both MELD (score > 21) and ALBI (score < -2.3) scores effectively predicted in-hospital mortality.
• Neither score accurately predicted hospitalization or early rebleeding. MELD score predicted mortality during the initial discharge phase.

Conclusions:

• MELD and ALBI scores demonstrate utility in predicting short-term outcomes, including death and rebleeding, in patients with AUGIB and liver cirrhosis.
• The MELD score is recommended as a more precise prognostic indicator than the ALBI score for patients with advanced liver cirrhosis.