Pseudomonas-induced corneal ulcers associated with contaminated eye mascaras
Related Experiment Video
Updated: Aug 19, 2026
Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
Published on: July 10, 2018
Abstract:
Seven Pseudomonas-induced corneal ulcers were associated with the use of four brands of mascara contaminated with P. aeruginosa. In laboratory studies, preservative systems of three of the four brands were inadequate in comparison with a control mascara of known antimicrobial activity. If the corneal epithelium is scratched during the application of mascara, particularly if the applicator is old, the cornea should be treated immediately and the mascara cultured to detect Pseudomonas. The high incidence of recurrent corneal ulceration in cases of Pseudomonas-induced keratitis indicates that initial chemotherapy should be intensive and maintained until the lesion stabilizes.
Insights
Contaminated mascara caused Pseudomonas-induced corneal ulcers. Inadequate preservative systems in three brands allowed bacterial growth, highlighting risks associated with eye cosmetic use and potential contamination.
Area of Science:
- Ophthalmology
- Microbiology
- Public Health
Background:
- Corneal ulcers are serious eye infections that can lead to vision loss.
- Pseudomonas aeruginosa is a common bacterium that can cause opportunistic infections.
Observation:
- Seven cases of Pseudomonas-induced corneal ulcers were linked to the use of four specific mascara brands.
- Laboratory analysis revealed inadequate preservative systems in three of the four implicated mascara brands.
Findings:
- Pseudomonas aeruginosa contamination was confirmed in the mascaras.
- The preservative systems of the affected mascaras failed to inhibit bacterial growth effectively compared to a control.
- Risk increases if the corneal epithelium is compromised during mascara application, especially with older applicators.
Implications:
- Ophthalmic P. aeruginosa infections necessitate intensive, prolonged chemotherapy.
- Immediate medical treatment and culturing of mascara are recommended if corneal injury occurs during application.
- Cosmetic product safety and preservative efficacy are critical for preventing microbial keratitis.
