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Updated: Jan 18, 2026

In Vivo Osteo-organoid Approach for Harvesting Therapeutic Hematopoietic Stem/Progenitor Cells
Published on: February 16, 2024
Influence of therapeutic exercise on the symptomatology associated with hematopoietic stem cell transplantation
Antonio Chamorro Comesaña1, Noa Piñeiro Fernández1, Patricia Rodríguez Fernández1
1Unidad de Fisioterapia, Logopedia y Estimulación, Hospital Álvaro Cunqueiro, Vigo, España.
Abstract:
Hematopoietic stem cell transplantation (HSCT) is a therapy used for the treatment of numerous pathologies, mainly oncohematological ones it is associated with the appearance of toxicities that can delay the patient's recovery.
Objective:
To observe the effect of a therapeutic exercise (TE) program produces on the symptoms reported by patients undergoing HSCT 3 months after the transplant.
Patients And Methods:
Observational study in patients who underwent HSCT at the Álvaro Cunqueiro Hospital in Vigo between September 2020 and August 2021, with pre-admission assessment and 3 months post-transplant, using Edmonton Symptom Assessment System (ESAS) test. During their hospitalization, the patients followed the ET program based on the HSCT exercise guidelines from the Spanish Group for Transplantation and Cellular Therapy (GETH-TC).
Results:
A total of 34 patients participated, and improvements were observed in fatigue, drowsiness, shortness of breath, mood, nervousness and feeling of well-being.
Conclusions:
A therapeutic exercise program is safe, and may help reduce common symptoms in transplant patients. Exercise must be adapted to the specific situation of the patient throughout the transplant process.
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