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Updated: Jan 18, 2026

Corneal Donor Tissue Preparation for Endothelial Keratoplasty
Published on: June 12, 2012
Intracorneal hypopyon within a DSAEK graft.
Angelica Piccini1, Jia Yin1, Levi N Kanu1
1From the Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts (Piccini, Yin, Kanu); Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts (Yin, Kanu); Cooper Medical School of Rowan University, Camden, New Jersey (Piccini).
Intracorneal hypopyon, an unusual collection of inflammatory cells within the cornea, can occur after Descemet-stripping automated endothelial keratoplasty (DSAEK). Anterior segment optical coherence tomography (AS-OCT) is key to differentiating it from persistent infiltrates.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Infectious Keratitis
Background:
- Intracorneal hypopyon is a rare condition involving inflammatory cell accumulation within the cornea.
- Descemet-stripping automated endothelial keratoplasty (DSAEK) is a surgical procedure for corneal diseases.
- This case highlights an unusual presentation of intracorneal hypopyon within a DSAEK graft.

