Related Experiment Video
Updated: Jan 18, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Transcatheter closure of multiperforated atrial septal defect
Luis Cerdán Ferreira1, Georgina Fuertes Ferre1, Juan Sánchez-Rubio Lezcano1
1Servicio de Cardiología, Hospital Universitario Miguel Servet, Zaragoza, España Servicio de Cardiología Hospital Universitario Miguel Servet Zaragoza España.
Introduction And Objectives:
Multi-fenestrated atrial septal defects (mASD) pose both diagnostic and therapeutic challenges. This study aimed to compare the outcomes of transcatheter closure in patients with mASD vs those with a single ASD at our center.
Methods:
We conducted a retrospective, single-center study including adult patients who underwent transcatheter ASD closure from October 2014 through October 2024. Demographic, echocardiographic, and hemodynamic data were collected, with a the 6-month follow-up.
Results:
A total of 67 patients were included, 12 of whom (18%) exhibited mASD. Patients with mASD were younger (42 vs 54 years) and more frequently presented with an interatrial septal aneurysm (91% vs 27%; P = .001). The use of multiple occlusion devices was more common in patients with mASD (34% vs 4%; P = .008). Complications were rare (5.9%) and none occurred in the mASD group. Procedural outcomes, including residual shunt and right ventricular remodeling at the follow-up, were comparable between groups.
Conclusions:
Transcatheter closure of mASD is both a safe and feasible procedure, with clinical outcomes similar to those observed in patients with a single ASD.

