Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

476
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
476
Psychosurgery01:30

Psychosurgery

1.6K
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
1.6K
Drug Therapy01:28

Drug Therapy

246
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
246

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beyond fear circuits: multiscale neurobiological architecture of panic disorder.

Molecular psychiatry·2026
Same author

Unveiling the Multifaceted Networks of the Left DLPFC for Precision TMS Targeting.

bioRxiv : the preprint server for biology·2025
Same author

Comparison of effectiveness of common targeting heuristics in repetitive transcranial magnetic stimulation treatment of depression.

BMJ mental health·2025
Same author

Motor-evoked potentials as biomarkers for sexual arousal?

The journal of sexual medicine·2024
Same author

<i>N</i>-Acetylcysteine and a Specialized Preventive Intervention for Individuals at High Risk for Psychosis: A Randomized Double-Blind Multicenter Trial.

Schizophrenia bulletin open·2024
Same author

Effect of prefrontal transcranial direct current stimulation on sexual arousal: A proof of concept study.

Neurophysiologie clinique = Clinical neurophysiology·2023
Same journal

Associations of excessive smartphone duration and unlock frequency with non-suicidal self-injury in college students.

World journal of psychiatry·2026
Same journal

Electroencephalogram-guided anesthesia and postoperative anxiety and depression in elderly gastric cancer patients with sleep disorders.

World journal of psychiatry·2026
Same journal

Effect of a combined of positive emotion, engagement, relationships, meaning, and accomplishment-based mental health intervention and role model incentives.

World journal of psychiatry·2026
Same journal

Impact of motor anxiety on rehabilitation in elderly stroke patients: A retrospective study.

World journal of psychiatry·2026
Same journal

Electroacupuncture alleviates depression and gastrointestinal dysfunction by rebalancing GABAergic activity in the central amygdala.

World journal of psychiatry·2026
Same journal

Prevalence, severity, and risk factors for depressive and anxiety symptoms among adolescents: A cross-sectional study.

World journal of psychiatry·2026
See all related articles

Related Experiment Video

Updated: Jan 18, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

16.0K

Unmet needs in precision psychiatry.

Philipp G Sand1,2, Timm B Poeppl3,4, Vera Roessler5

  • 1Department of Psychiatry, University of Regensburg, Regensburg 93053, Bavaria, Germany.

World Journal of Psychiatry
|September 11, 2025
PubMed
Summary
This summary is machine-generated.

A specific gene variant (5-HTR1A) may not reliably predict antidepressant response due to significant data errors and methodological issues. Further research is needed to ensure genetic data accuracy for personalized psychiatry.

Area of Science:

  • Pharmacogenetics
  • Psychiatric Genetics
  • Molecular Psychiatry

Background:

  • A meta-analysis suggested the 5-HTR1A promoter variant predicts antidepressant response.
  • This review critically examines the validity of these claims.
Keywords:
5-HTR1A geneAntidepressant efficacyC-1019G polymorphismMajor depressive disorderMeta-analysis

More Related Videos

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

14.5K
Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

19.0K

Related Experiment Videos

Last Updated: Jan 18, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

16.0K
MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

14.5K
Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

19.0K