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HEAVY VERSUS STANDARD SILICONE OIL TAMPONADE IN PRIMARY RETINAL DETACHMENT SURGERY: A Systematic Review and
Matteo Mario Carlà1,2, Carlos Mateo3, Tomaso Caporossi2,4
1Ophthalmology Department, "Fondazione Policlinico Universitario A. Gemelli, IRCCS", Rome, Italy.
Retina (Philadelphia, Pa.)
|September 11, 2025
Summary
Heavy silicone oil (HSO) and standard silicone oil (SSO) show similar success in treating rhegmatogenous retinal detachment (RRD). However, HSO is linked to increased intraocular pressure and emulsification risks.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Vitreoretinal Interface
Background:
- Rhegmatogenous retinal detachment (RRD) is a sight-threatening condition requiring prompt surgical intervention.
- Silicone oil tamponade is a common technique used in complex RRD repair.
- Heavy silicone oil (HSO) and standard silicone oil (SSO) are two types of tamponades with distinct physical properties.
Purpose of the Study:
- To compare the anatomical and functional outcomes of HSO versus SSO in primary RRD.
- To evaluate and contrast postoperative complications associated with HSO and SSO tamponades.
Main Methods:
- A systematic meta-analysis was conducted following PRISMA guidelines.
- Relevant studies published between 2000 and present were retrieved from major databases (PubMed, Embase, Cochrane, Scholar, Web of Science).
- Included studies focused on primary success rates, best-corrected visual acuity (BCVA) improvement, and postoperative complications in patients undergoing HSO or SSO tamponade for RRD.
Main Results:
- Six studies involving 984 eyes were analyzed, comparing HSO and SSO.
- Both HSO and SSO demonstrated comparable primary anatomic success rates.
- While visual acuity improvement was similar, HSO was associated with significantly higher rates of intraocular pressure (IOP) elevation and silicone oil emulsification.
Conclusions:
- HSO and SSO offer similar anatomical success rates for primary RRD repair.
- Visual outcomes are comparable between HSO and SSO, despite potential baseline limitations.
- HSO use is associated with an increased risk of postoperative IOP elevation and emulsification compared to SSO.

