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From Kratom to Semi-Synthetic Opioids: The Rise and Risks of MGM-15

Abhishek Gour1, Sushobhan Mukhopadhyay2, Allison Henderson1

  • 1Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.

Drug Testing and Analysis
|September 12, 2025
PubMed
Summary

Synthetic kratom alkaloid MGM-15, found in research chemical tablets, exhibits higher opioid receptor binding than 7-hydroxymitragynine (7-HMG). This indicates potential for increased opioid effects and risks, necessitating further research for regulation and harm prevention.

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