Subjective Grading and Objective Assessment After Switching to a Daily Disposable Silicone Hydrogel Contact Lens

To evaluate both subjective grading and objective assessments associated with switching from habitual silicone hydrogel daily disposable contact lenses to verofilcon A lenses (study lenses) among young Asian individuals, and to investigate the relationship between these subjective and objective measures.

58 participants wore study lenses for 8-10 hours daily for a week. Subjective assessments, including comfort, visual quality, and eye dryness, were conducted using a numerical rating scale (0-100) on the first and seventh day. Noninvasive tear breakup time (NITBUT), bulbar conjunctival redness (BR), tear meniscus height (TMH), and meibography were measured with the Keratograph M5 at baseline, the first and the seventh day.

After the seventh day, subjective ratings showed increased comfort and decreased visual quality and dryness. Comfort and visual quality scores on the first and seventh days were above 85 points, with no significant differences. The average NITBUT significantly improved 15 minutes and 8 hours post-lens application compared to baseline measures (P = 0.019). Tear meniscus height was highest at baseline, with a marginal decrease observed following both 15 minutes and 8 hours of study lenses wear (P < 0.001). The most pronounced bulbar conjunctival redness was noted at baseline, decreasing significantly after switching to study lenses (P = 0.002). Notably, NITBUT was found to be significantly positively correlated with comfort (P < 0.05).

The switch to daily disposable study lenses resulted in maintained comfort and improved tear film stability in the young Asian population. A significant positive correlation was observed between NITBUT and subjective measures of comfort.