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Updated: Jan 18, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
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[Infections with cardiac implantable electronic device].

Ava Azari1, Ingibjörg Kristjánsdóttir2, Paolo Gatti3

  • 1leg läkare, -Karolinska universitets-sjukhuset, Stockholm; -institutionen för medicin, -Karolinska institutet.

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Summary
This summary is machine-generated.

Lead extraction is safe for patients with device infections. Systemic infection, kidney disease, and frailty are key mortality risks to consider before the procedure.

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Device Management

Background:

  • Cardiac implantable electronic devices (CIEDs) are crucial for managing cardiac conditions.
  • Infections associated with CIEDs pose significant risks, including systemic and local spread.
  • Lead extraction is a complex procedure with potential risks and benefits.

Purpose of the Study:

  • To evaluate the safety and effectiveness of lead extraction in patients with CIED infections.
  • To identify mortality risk factors associated with lead extraction in this patient population.
  • To inform pre-procedure risk stratification strategies for CIED lead extraction.

Main Methods:

  • Retrospective analysis of patients undergoing CIED lead extraction due to systemic or local infections.
  • Assessment of 30-day and 1-year mortality rates.
  • Statistical analysis to identify independent predictors of mortality, including comorbidities and frailty.

Main Results:

  • Lead extraction demonstrated safety and effectiveness in patients with CIED infections.
  • The 30-day mortality rate was 2.5%, and the 1-year mortality rate was 9.9%.
  • Systemic infection, chronic kidney disease, and frailty (Clinical Frailty Scale 5-7) were independently associated with increased mortality.

Conclusions:

  • Lead extraction is a viable option for managing CIED infections.
  • Identifying patients with systemic infection, chronic kidney disease, or significant frailty is crucial for risk stratification.
  • Pre-procedure assessment of these risk factors can optimize patient selection and management for lead extraction.