Orbital Castleman Disease on 18 F-FDG PET/CT.

Area of Science:

• Ophthalmology
• Nuclear Medicine
• Pathology

Background:

• Castleman disease is a rare lymphoproliferative disorder.
• Orbital involvement is exceptionally uncommon.
• Accurate diagnosis is crucial for appropriate management.

Purpose of the Study:

• To describe the 18F-FDG PET/CT imaging characteristics of orbital Castleman disease.
• To highlight the utility of PET/CT in diagnosing this rare orbital mass.

Main Methods:

• Case report of a 48-year-old female patient.
• Utilized 18F-FDG PET/CT for imaging the right orbit.
• Pathologic examination confirmed the diagnosis.

Main Results:

• PET/CT demonstrated a soft tissue mass within the right orbital muscle cone.
• The mass exhibited significantly elevated 18F-FDG uptake.
• Histopathology confirmed hyaline vascular type Castleman disease.

Conclusions:

• 18F-FDG PET/CT can effectively detect and characterize orbital Castleman disease.
• This imaging modality aids in the diagnosis of rare orbital pathologies.
• Hyaline vascular type is a possible diagnosis for hypermetabolic orbital masses.