Daily Mango Intake Improves Glycemic and Body Composition Outcomes in Adults with Prediabetes: A Randomized...

Area of Science:

• Nutrition Science
• Metabolic Health
• Dietary Interventions

Background:

• Prediabetes prevalence is increasing, posing risks for type 2 diabetes and cardiometabolic complications.
• Dietary interventions are crucial for managing blood glucose and body composition in prediabetes.
• Evaluating whole foods like mango for their metabolic effects is important.

Purpose of the Study:

• To investigate the effects of daily fresh mango consumption on glycemic control and body composition in adults with prediabetes.
• To compare mango intake against an isocaloric control intervention over 24 weeks.

Main Methods:

• Randomized controlled trial with 23 participants (11 mango, 12 control).
• Treatment group consumed ~300g fresh mango daily for 24 weeks.
• Control group consumed an isocaloric granola bar daily for 24 weeks.
• Measurements included anthropometrics, body composition, and blood markers at baseline and weeks 6, 12, and 24.

Main Results:

• Mango group showed significantly lower fasting blood glucose and improved insulin sensitivity (QUICKI) at 24 weeks.
• A trend towards lower insulin resistance (HOMA-IR) was observed in the mango group.
• HbA1c remained stable in the mango group, while it increased in the control group.
• The mango group exhibited a borderline decrease in body fat percentage and an increase in fat-free mass.

Conclusions:

• Daily mango consumption for 24 weeks positively influenced glycemic control and insulin sensitivity in prediabetic adults.
• Mango intake also led to favorable changes in body composition, including reduced body fat and increased lean mass.
• Mango shows potential as a practical and effective dietary strategy for improving metabolic health in individuals with prediabetes.