Related Experiment Video
Updated: Jun 17, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Tibial Anterior Cruciate Ligament Avulsion Fractures in Pediatric and Adult Populations: A Systematic Literature
Vincent Landré1, Michel Teuben1, Felix Karl-Ludwig Klingebiel1
1Department of Traumatology, University Hospital Zurich, University Zurich, Raemistrasse 100, 8091 Zurich, Switzerland.
Abstract:
Objectives: Tibial anterior cruciate ligament avulsion fractures (TAFs) are avulsions of the anterior cruciate ligament (ACL) from its insertion at the tibial intercondylar eminence that share the same trauma mechanism as ACL tears. TAFs were initially considered to be a pediatric equivalent to adult ACL ruptures due to the weaker insertion of the ACL on the immature tibial spine. Recent literature suggests that adult TAFs may be more common than previously thought. The incidence, possible concomitant injuries, and other differences between pediatric and adult TAFs remain a topic of ongoing debate in the literature. This systematic review provides a descriptive synthesis of the symptoms, biomechanics, and treatment outcomes of TAFs in pediatric and adult populations. This study highlights notable trends but avoids formal comparisons or meta-analysis due to heterogeneity in the literature. Methods: A systematic review was conducted on human-related studies involving tibial anterior cruciate ligament avulsion fractures, identified in PubMed®® and EMBASE®® databases between 2000 and 2024. Studies in English or German were included, while editorials, reviews, experimental studies, and papers with insufficient data were excluded. Data were extracted on patient demographics, trauma mechanisms, fracture classification, diagnostic modalities, treatment approaches, and clinical outcomes. Specific outcome parameters included: incidence and type of postoperative complications, return to sport rate, revision surgeries, hardware removal rates, and duration of follow-up. Due to heterogeneity in reporting, a descriptive synthesis approach was used rather than a meta-analysis. Results: The systematic search identified 3938 publications, with 2707 articles screened after duplicate removal. A total of 56 studies met the inclusion criteria. A total of 677 tibial avulsion fractures (TAF) were analyzed, with 208 (30.4%) pediatric and 469 (69.6%) adult patients. Type III fractures were most common in both groups (pediatric: 63.9%, adult: 63.4%). Concomitant injuries were more frequent in adults (35.6%) than children (8.2%). Arthroscopic surgery was the predominant technique (pediatric: 79.1%, adult: 87.8%). Fixation methods differed: pediatric cases more often used screws (40.5%) and sutures (38.2%), while adults favored sutures (49.7%) and suture anchors (23.1%). Complications were more frequent in pediatric patients (35.1% vs. 17.1%). Conclusions: TAFs show age-related differences in injury patterns and outcomes. Pediatric cases are mostly sports-related, while adult cases are commonly due to road traffic accidents. Concomitant injuries are more frequent in adults, whereas pediatric patients experience higher rates of arthrofibrosis and instability. Adults are more prone to malunion and non-union. These findings support the need for age-specific diagnostic and treatment strategies.
More Related Videos
05:44Author Spotlight: Double Posteromedial Approach for Treating Posterior Cruciate Ligament Cysts
Published on: October 20, 2023
06:28Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis
Published on: September 2, 2025
Related Concept Videos
What is the Skeletal System?
Osteoclasts in Bone Remodeling
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Introduction to the Skeletal System
Components of the Skeletal System
Bone, or osseous tissue, is a hard connective tissue that forms an internal support structure for the human body. Bones shield vulnerable organs and soft tissue from external forces. For example, the vertebral bones protect and support the spinal cord.
Cartilage, a semi-rigid connective tissue found in regions such as...