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Diabetes and the heart

Andrew J Sullivan1, Andrew Wragg1, Krishnaraj Rathod1

  • 1Barts Heart Centre, St. Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, United Kingdom; Barts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, United Kingdom.

Clinical Medicine (London, England)
|September 13, 2025
PubMed

Insights

Diabetes (diabetes mellitus) and heart disease often occur together. This review covers common heart issues in diabetes, diagnostic methods, and management strategies for better patient outcomes.

Area of Science:

  • Cardiology
  • Endocrinology
  • Internal Medicine

Background:

  • Diabetes mellitus and cardiac conditions frequently coexist.
  • This comorbidity presents significant clinical challenges for healthcare providers.
  • Effective management requires understanding the interplay between these conditions.

Purpose of the Study:

  • To review common cardiac manifestations in patients with diabetes mellitus.
  • To outline diagnostic strategies and management approaches for these conditions.
  • To discuss cardiovascular risk stratification and glucose-lowering therapies with cardiovascular benefits.

Main Methods:

  • Literature review of common cardiac issues in diabetes.
  • Discussion of diagnostic tools and therapeutic interventions.
  • Analysis of risk stratification and pharmacotherapy for cardiovascular protection.

Main Results:

  • Common cardiac manifestations include coronary artery disease, heart failure, and arrhythmias.
  • Specific diagnostic pathways and management protocols are detailed.
  • Cardiovascular risk stratification and glucose-lowering agents with proven benefits are highlighted.

Conclusions:

  • A holistic, patient-centered approach is essential for managing co-existent diabetes and cardiac problems.
  • Tailoring treatment strategies to individual patient needs is crucial.
  • Integrated care improves outcomes for patients with both conditions.

Keywords:
Cardiovascular diseasesDiabetes mellitusHeart diseasesHeart failureMyocardial ischaemia

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