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A Way With Words: Do Clinicians Talk Differently When Assessing Autism in Boys vs Girls?
Julia Parish-Morris1, Meredith Cola2, Julia Parish-Morris
1Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania.
Insights
Autism presents differently in females, leading to underdiagnosis. More research is needed to understand sex-specific traits and improve diagnostic tools for autistic individuals.
Area of Science:
- Neurodevelopmental Disorders
- Autism Spectrum Disorder (ASD) research
- Pediatric Neurodevelopment
Background:
- Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition affecting social communication and behavior.
- ASD is diagnosed less frequently and at later ages in females compared to males.
- Current diagnostic tools may not adequately capture the presentation of autism in females.
Abstract:
Autism is a complex, heterogeneous neurodevelopmental condition that affects 1 in 31 children,1 and is characterized by social communication challenges and the presence of restricted and/or repetitive patterns of behaviors and interests.2 Autism is diagnosed at a significantly lower rate and at later ages in autistic female individuals than in autistic male individuals.3 These sex-based diagnostic discrepancies may be due, in part, to a poor understanding of how autism presents in female individuals,4 underrecognition of autistic traits that have an impact on female individuals' likelihood of being referred for an autism evaluation, and a paucity of diagnostic tools that are sensitive to sex-specific behavioral presentations.5 Notably, gold-standard diagnostic tools were developed on disproportionately male samples, leading to concerns that autistic in female individuals could be underdiagnosed when using these measures.6.
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