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Case Volume and Experience in Stereotactic Radiation: Analysis of a Prospective Peer Review Program
Luke Peng1, Kee-Young Shin2, Tara Kosak1
1Department of Radiation Oncology, Dana-Farber Brigham Cancer Center, Boston, Massachusetts.
Advances in Radiation Oncology
|September 15, 2025
Summary
Prospective peer review of stereotactic radiation therapy (SRT) plans is crucial. Higher case volume and physician experience are linked to fewer SRT plan revisions, suggesting these factors improve treatment quality.
Area of Science:
- Radiation Oncology
- Medical Physics
- Clinical Research
Background:
- Stereotactic radiation therapy (SRT) offers high efficacy but poses risks of significant toxicity.
- Prospective peer review is essential for optimizing SRT treatment plans and patient safety.
Purpose of the Study:
- To identify factors associated with SRT plan revisions within a prospective peer review program.
- To evaluate the impact of physician experience and case volume on SRT plan quality.
Main Methods:
- A prospective peer review program involving weekly rounds for SRT cases was established.
- Case revision recommendations were tracked, and logistic regression analysis was used to identify significant factors.
- Data included 1172 SRT cases (SRS, multi-fractionated SRS, stereotactic body radiation therapy) reviewed between 2019 and 2024.
Main Results:
- The yearly revision rate varied from 19% to 31% over the study period.
- Multivariable analysis revealed that high-volume physicians (OR, 0.58) and those with 3-9 years of experience (OR, 0.65) were less likely to have plans revised.
- Stereotactic radiosurgery (SRS) technique was also associated with fewer revisions (OR, 0.59).
Conclusions:
- Prospective peer review is highly valuable, particularly for physicians with low case volume and early in their careers.
- Adequate case volume appears critical for high-quality SRT, similar to findings in surgical literature.
- Substantial annual revision rates underscore the continued importance of robust prospective peer review for SRT.

