Related Experiment Video
Updated: Jan 17, 2026

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
Published on: December 1, 2023
Effect of nine different exercise interventions on insulin sensitivity in diabetic patients: a systematic review and
Yikang Pan1, Peng Wang1, Chunlin Yue2
1Sports Department, Changzhou Vocational Institute of Textile and Garment, Changzhou, Jiangsu, China.
Objective:
This study aimed to assess the impact of nine exercise interventions (resistance training [BT, ball training [BT], resistance + walking [RT+W alk], resistance + running [RT + Running], resistance + cycling [RT + bicycle], running, and Tai Chi) on insulin sensitivity in patients with diabetes.
Methods:
A systematic search of five databases (PubMed, EMBASE, Cochrane, Web of Science, and CNKI) for RCTs investigating the effects of exercise interventions on insulin sensitivity in patients with diabetes was conducted. The quality of the included studies was assessed using the Cochrane Manual version 5.1.0 Risk of Bias Assessment Tool (ROB). Data analysis software was used for the synthesis and analysis.
Results:
This Meta-analysis comprised 21 randomized controlled trials involving 1140 participants. Cycling significantly reduced the fasting glucose index in individuals with diabetes (SUCRA score=90.7%). Resistance exercise exhibited superior efficacy in enhancing insulin sensitivity compared with alternative interventions in patients with diabetes (SUCRA score=71.8%). Furthermore, the combination of resistance exercise and running resulted in a noteworthy decrease in HOMA-IR levels (SUCRA score=64.2%).
Conclusion:
Cycling, resistance training, and combined aerobic and resistance exercises have been shown to effectively enhance fasting blood glucose levels, insulin secretion, and insulin sensitivity in individuals with diabetes. However, additional studies with longer follow-up periods and more rigorous methodologies are required to further validate these findings.
Systematic Review Registration:
https://ww.crd.york.ac.uk/PROSPERO/, identifier CRD42023450107.
More Related Videos
Related Concept Videos
Oral Hypoglycemic Agents: Biguanides and Glitazones
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Dipeptidyl Peptidase 4 Inhibitors
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...

