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Safety and Efficacy of the Corheart 6 Left Ventricular Assist System

Zhibing Qiu1, Xiaochun Song, Hongwei Shi

  • 1From the Department of Cardiothoracic and Vascular Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|September 15, 2025
PubMed

Insights

The Corheart 6 Left Ventricular Assist System (LVAS) shows promising mid-term survival and improved cardiac function in end-stage heart failure patients. Its safety profile is manageable, with no device malfunctions reported.

Area of Science:

  • Cardiology
  • Medical Devices
  • Mechanical Circulatory Support

Background:

  • End-stage heart failure necessitates advanced therapeutic options.
  • Left Ventricular Assist Systems (LVAS) offer a critical solution for patients awaiting transplant or as destination therapy.

Purpose of the Study:

  • To evaluate the efficacy and safety of the Corheart 6 LVAS.
  • To assess clinical outcomes, including survival and cardiac function, in patients with end-stage heart failure receiving the Corheart 6 LVAS.

Main Methods:

  • Retrospective cohort study at Nanjing First Hospital (March 2022 - March 2024).
  • Enrolled 28 patients with end-stage heart failure implanted with Corheart 6 LVAS.
  • Primary endpoint: 6-month survival free from disabling stroke.

Main Results:

  • 100% survival at 3 months, 89.3% at 6 months (3 deaths).
  • Significant improvements in cardiac function observed post-implantation.
  • No pump thrombosis, hemolysis, or device malfunction; stable hemolysis markers.

Conclusions:

  • Corheart 6 LVAS demonstrates favorable mid-term survival and cardiac functional improvement.
  • The device presents a manageable safety profile for critically ill heart failure patients.
  • Further investigation into managing adverse events like infections and arrhythmias is warranted.

Keywords:
Corheart 6adverse eventscardiac functionheart failureleft ventricular assist devicesurvival

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