Related Experiment Video
Updated: Jan 6, 2026

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
Re: ID f1459919-55b0-4cf8-8c61-369db603bc92 echocardiography in collagen diseases
Takahide Ito1, Kanako Akamatsu2, Hideaki Morita2
1Department of Cardiology, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-machi, Osaka, 569-8686, Takatsuki, Japan. takahide.ito@ompu.ac.jp.
Collagen diseases can affect the heart, leading to complications like pulmonary hypertension and heart dysfunction. Advanced echocardiography helps detect these subclinical cardiac changes early.
Area of Science:
- Cardiology
- Rheumatology
- Medical Imaging
Background:
- Collagen diseases are chronic inflammatory disorders affecting connective tissues.
- Cardiac involvement is frequent, with pulmonary hypertension being a common complication.
- Echocardiography aids in detecting subclinical cardiac changes.
Purpose of the Study:
- To present characteristic echocardiographic findings in various collagen diseases.
- To highlight the utility of echocardiography in diagnosing cardiac complications.
- To provide visual examples of echocardiographic features.
Main Methods:
- Review of echocardiographic findings in patients with collagen diseases.
- Application of advanced echocardiographic techniques like exercise, speckle tracking, and 3D echocardiography.
- Correlation of echocardiographic findings with specific collagen disease manifestations.
Main Results:
- Systemic sclerosis: Exercise echocardiography detects pulmonary artery hypertension; speckle tracking assesses right ventricular overload.
- Systemic lupus erythematosus: 3D echocardiography improves visualization of Libman-Sacks endocarditis.
- Dermatomyositis/Rheumatoid Arthritis: Associated with pericardial effusion, diastolic dysfunction, and myocardial hypertrophy.
Conclusions:
- Echocardiography is crucial for identifying and characterizing cardiac involvement in collagen diseases.
- Specific echocardiographic techniques offer valuable insights into disease severity and progression.
- Early detection of cardiac complications through echocardiography can guide patient management.
Related Concept Videos
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Acute Coronary Syndrome III: Diagnostic Studies

