Treatment-associated posterior reversible encephalopathy syndrome in an adolescent with Crohn's disease: A case report

Posterior reversible encephalopathy syndrome (PRES) is a type of leukoencephalopathy that usually presents symptoms such as headache, altered consciousness, seizures, blurred vision, and imaging signs such as subcortical white matter edema, predominantly in the parieto-occipital lobes. Numerous risk factors have been identified, which involve impaired cerebral blood flow autoregulation and vasogenic edema. We present the case of a 14-year-old female patient who, in the context of an induction treatment for Crohn's disease with high-dose corticosteroids, azathioprine, and infliximab, presented with posterior reversible encephalopathy, a rare complication in patients with inflammatory bowel disease.