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High-Precision Refractive Index-Based Microparticle Sorting Using Airy Beams
Zhelin Qu1, Yanan Zhang2, Kunpeng Wang1
1Center for Optics Research and Engineering, MOE Key Laboratory of Infrared and Laser Systems, Shandong University, Qingdao 266000, China.
Analytical Chemistry
|September 16, 2025
Summary
This study introduces Airy beams for precise microparticle sorting based on refractive index. The method achieves label-free, contactless separation of particles with subtle refractive index differences, advancing diagnostics and material identification.
Area of Science:
- Optics and Photonics
- Microfluidics
- Biotechnology
Background:
- Accurate microparticle sorting by refractive index is vital for diagnostics and material science.
- Conventional methods lack precision for particles with similar sizes but differing compositions.
Purpose of the Study:
- To develop a high-precision, label-free, and contactless method for refractive index-based microparticle sorting.
- To utilize the unique properties of Airy beams for enhanced particle manipulation.
Main Methods:
- Employing Airy beams, which exhibit lateral acceleration and nondiffractive propagation.
- Demonstrating sorting capabilities for particles with refractive index differences as low as 0.03.
Main Results:
- Successful separation of various microparticles (polystyrene, PVC, silica, PMMA) based solely on refractive index.
- Achieved robust and precise sorting in a label-free and contactless manner.
Conclusions:
- Airy beam-based sorting offers a versatile and efficient tool for microparticle manipulation.
- Potential applications include advanced particle characterization, bioseparation, and microfluidic systems.

