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A Rare Presentation of Adult Primary Leptomeningeal Medulloblastoma: Case Report

Grace E Hey1, Megan E H Still2, Rachel S F Moor2

  • 1University of Florida College of Medicine, Gainesville, Florida, USA.

Case Reports in Pathology
|September 17, 2025
PubMed

Insights

This study reports a rare case of primary spinal leptomeningeal medulloblastoma in an adult woman. This finding expands understanding of medulloblastoma presentation beyond the posterior fossa.

Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Pathology

Background:

  • Medulloblastomas typically arise in the posterior fossa and can spread to the leptomeninges.
  • Primary leptomeningeal medulloblastoma, especially in the spine without cranial involvement, is exceptionally rare in adults.
  • Medulloblastoma constitutes a small fraction of adult brain tumors.
Keywords:
leptomeningeal medulloblastomamedulloblastomaneuro-oncologyneurosurgery

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